SUPPLEMENT COMPARISON - UPDATED MARCH 2026
Coastline vs AG1: Which Longevity Supplement Is Actually Worth It?
Both brands promise better health. But which one actually delivers? We compared ingredients, clinical evidence, pricing, and real user feedback.
By Dr. James Chen
Clinical Nutrition Researcher
Coastline
13 clinical-dose ingredients
AG1
75 ingredients, doses undisclosed
The supplement market has exploded. AG1 has dominated with aggressive marketing and influencer partnerships. But several science-first alternatives have emerged. Coastline is one of them.
The study AG1 probably wishes you had not seen
For years, AG1 has been the default recommendation. You have seen it everywhere -- podcast ads, YouTube sponsorships, Instagram stories. It became the supplement that people bought because everyone else seemed to be buying it.
Then AG1 published its own clinical trial. The results were supposed to validate what millions of subscribers already believed. Instead, the data told a very different story.
Here is what the study actually found -- and why it matters for anyone paying $79 a month.
The Clinical Evidence
AG1's Own Clinical Trial Found:
- ✗ No significant changes in blood biomarkers vs placebo
- ✗ No statistically significant gut health improvement (p = 0.058)
- ✗ No metabolic or inflammatory benefits detected
- ✗ Microbiome changes were clinically irrelevant
- ✗ Placebo showed similar or larger shifts
“I'd cancel your AG1 subscription.”
-- Bryan Johnson, tech entrepreneur and longevity advocate
The pixie dusting problem
AG1 contains 75 ingredients in a single scoop. That sounds impressive until you do the math. Imagine splitting a single glass of water among 75 people. Each person gets a few drops. That is what happens when you cram 75 ingredients into one serving -- most are present in trace amounts far below what clinical trials use.
So we pulled the data
That is a lot to take in. A product used by millions, backed by some of the biggest names on the internet, and its own clinical trial could not demonstrate significant benefits over a placebo.
So we did what any rational person would do. We pulled the publicly available data on both AG1 and Coastline and laid them side by side. Not marketing claims. Just the ingredients, the doses, the clinical evidence, and the price.
Here is exactly what we found when we compared them head to head.
Price Comparison
What you're actually paying for
AG1
$79/month
75 ingredients at trace amounts
~$1.05 per ingredient per month
$2.63/day
$948/year
Proprietary blends -- doses undisclosed
Coastline
$99/month
13 ingredients at clinical doses
~$7.62 per ingredient per month
$3.30/day
$1,188/year
Full transparency -- every dose disclosed
$0.67/day more for ingredients proven to work at doses proven to matter. You are not paying for ingredient count. You are paying for ingredient doses that actually work.
Ingredient Comparison
Side by side
| Coastline | AG1 | |
|---|---|---|
| Clinical dosing | ✓ Full transparency | ✗ Proprietary blends |
| Ingredient count | 13 (precision) | 75 (pixie dusting) |
| Inulin dose | 4g (clinical dose) | Undisclosed |
| Creatine | 5.25g | None |
| CoQ10 | 200mg | None |
| Taurine | 3.05g | None |
| AM/PM timing | ✓ Yes | ✗ No |
| Hallmarks of aging | All 12 | ~3-4 |
| Body systems | 11 | 6 |
| Caffeine-free | ✓ | ✓ |
| Vegan | ✓ | ✓ |
| Clinical trial | Individual ingredients proven | No significant benefit |
| Dose transparency | Full disclosure | Proprietary blends |
AG1 Claims
"Supports energy, focus, gut health." Vague language with no specific doses, no specific studies cited, and no measurable outcomes defined.
Coastline Delivers
- ✓ Taurine at 3.05g -- supports cardiovascular health and extends lifespan in animal models
- ✓ Creatine at 5.25g -- increases muscle strength and sharpens cognition
- ✓ Inulin at 4g -- feeds beneficial gut bacteria and supports digestion
- ✓ CoQ10 at 200mg -- supports cellular energy and mitochondrial function
- ✓ Glycine at 5g -- improves sleep quality and reduces inflammation
- ✓ Astaxanthin at 6mg -- one of the most potent antioxidants known to science
- ...and 7 more clinically dosed ingredients. Every dose backed by specific trials.
What is actually inside each product
The comparison table tells one story. But numbers on a page do not show you what is actually going into your body every morning and every evening.
Coastline is built around 13 specific compounds -- each selected because the clinical evidence was too strong to ignore. Not 75 ingredients sprinkled in at trace amounts. Thirteen. Every single one at the dose used in the studies that proved it works.
Here is exactly what is in the formula, how it is organized, and why each ingredient made the cut.
The Coastline Formula
13 ingredients. Every dose disclosed.
Three products. One system. Optimized for your circadian rhythm.
Morning
Powder Blend - 7 Ingredients
Ergothioneine
5 mg -- crosses blood-brain barrier
Taurine
3.05 g -- cardiovascular and lifespan support
Creatine Monohydrate
5.25 g -- muscle strength and cognition
Glycine
5 g -- sleep quality and blood sugar
Inulin
4 g -- prebiotic gut health
Magnesium (Citrate)
150 mg -- 300+ enzyme cofactor
Glucosamine Sulfate
750 mg -- joint health (AM dose)
Morning
Softgels - 4 Ingredients
Astaxanthin
6 mg -- potent antioxidant
Lutein
10 mg -- eye and brain health
Zeaxanthin
2 mg -- macular protection
Coenzyme Q10
200 mg -- cellular energy
Evening
Capsules - 3 Ingredients
Lithium (as Orotate)
400 mcg -- neuroprotection
L-Theanine
200 mg -- calm without grogginess
Glucosamine Sulfate
750 mg -- joint health (PM dose)
Coastline includes clinical-dose inulin at 4g -- the very prebiotic Bryan Johnson recommends -- as just one of 13 ingredients.
Built by researchers, not marketers
We did not design this formulation in isolation. Coastline was built alongside a team of researchers and clinicians with decades of combined experience in circadian biology, molecular medicine, and human performance.
Their job was simple: review thousands of studies and identify the compounds with the strongest evidence for human longevity. Not trends. Not marketing-friendly superfoods. Just what actually works, at doses that actually matter. Here is what they have to say about the result.
WHAT RESEARCHERS SAY
Greg Potter, PhD, MSc
Sleep & Circadian Health
The 13 ingredients chosen for Coastline are the most scientifically supported, and clinically validated supplements yet to be discovered.
Dr. Jacqueline Jacques, ND
Naturopathic Medicine
Coastline is what happens when you combine scientific rigor with real-world clinical understanding.
Dr. Nicolas Verhoeven, PhD
Molecular Medicine
I value Coastline's quality. It means less hassle with the greatest certainty.
Chris Pollock, MD
Internal Medicine
A comprehensive, evidence-based approach to longevity that I recommend to my patients.
What real customers are saying
Expert validation matters. But at the end of the day, what matters most is whether real people notice a real difference. Not in a lab. In their actual lives -- their mornings, their workouts, their energy at 3 PM, their sleep.
We asked Coastline customers to share their experience. Many of them came from AG1 or other supplements. Some are physicians. Some are athletes. Some are parents who just wanted to stop feeling exhausted. Here is what they said.
REAL REVIEWS
People who made the switch
As a physician, I'm skeptical of most supplements. But the science behind Coastline convinced me. Three months in, my biomarkers have never looked better.
Michael R., 62 - Physician
Physician
Quality you can feel. You can tell this was made by scientists, not a marketing team.
Edward Q., 49
Richmond, VA
I used to spend over $200 a month on five different supplements and still was not sure I was covering everything. Coastline replaced all of them. One system, done.
Lisa T., 52
Austin, TX
I'm extremely careful about what I put in my body. Coastline checked every box for purity and data.
Rachel G., 48
Boulder, CO
I love the convenience of having everything I need in one simple system. No more pill organizers.
James U., 44
Tampa, FL
Finally, a longevity stack that does not require 15 different bottles. My morning brain fog is gone.
Robert K., 45
Chicago, IL
Three weeks in and the mental sharpness is unmistakable. I'm writing better code, retaining more from meetings, and my afternoon crash is just gone.
Thomas H., 43
Atlanta, GA
I stopped needing my second coffee by week two. The energy is steady -- no spike, no crash. Just consistent output from 6 AM to 10 PM.
Derek W., 47
Scottsdale, AZ
As a busy mother and entrepreneur, mental clarity is my most valuable asset. Coastline cleared the afternoon fog that I thought was just a permanent part of my life.
Sophia R., Founder
Founder, New York
I ran every ingredient through PubMed before buying. Every single one checks out at clinical doses. That never happens with supplement companies.
Andrew P., 55
Boston, MA
I train six days a week and recovery used to be my biggest bottleneck. Since starting Coastline, I'm bouncing back faster and my endurance has noticeably improved.
Marcus D., 39
Denver, CO
My naturopath actually recommended Coastline after reviewing the ingredient list. That kind of third-party validation sealed the deal for me.
Catherine W., 58
Seattle, WA
My husband and I both switched to Coastline. We cancelled six separate subscriptions between us. Simpler, cheaper, and we actually feel the difference.
Christine A., 49
Denver, CO
At 72, I'm still active and working. Coastline helps me keep pace with people half my age.
Arthur B., 72
Palm Springs, CA
Morning scoop, one softgel, two capsules before bed. That's it. I replaced an entire shelf of bottles with one system.
Kevin M., 40
Nashville, TN
The final scorecard
The customer reviews paint a consistent picture. But we wanted to go one step further and give you a clear, side-by-side rating across every dimension that actually matters when choosing a longevity supplement.
We evaluated both products on ingredient quality, clinical evidence, dose transparency, value per ingredient, and overall convenience. Here is the final scorecard.
Summary
The verdict
| Coastline | AG1 | |
|---|---|---|
| Ingredient quality | ★★★★★ | ★★☆☆☆ |
| Clinical evidence | ★★★★★ | ★☆☆☆☆ |
| Dose transparency | ★★★★★ | ★☆☆☆☆ |
| Value per ingredient | ★★★★★ | ★★☆☆☆ |
| Convenience | ★★★★☆ | ★★★★☆ |
| Overall | ★★★★★ | ★★☆☆☆ |
Key Takeaways
- ✓ AG1's own clinical trial found no significant benefits over placebo across blood biomarkers, gut health, and metabolic markers.
- ✓ AG1 uses 75 ingredients in proprietary blends with undisclosed doses. Coastline uses 13 ingredients at full clinical doses with complete transparency.
- ✓ Coastline costs $0.67/day more ($3.30 vs $2.63) but delivers clinically validated doses of every ingredient.
- ✓ Coastline uses an AM/PM system timed to your circadian biology. AG1 is a single scoop with no timing optimization.
- ✓ Coastline targets all 12 hallmarks of aging across 11 body systems. AG1 addresses roughly 3-4 hallmarks.
READY TO SWITCH?
Ready to make the switch?
If you have been paying $79/month for AG1 and want ingredients that actually work at doses that actually matter, Coastline might be worth trying.
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Risk-Free Guarantee
- ✓ 60-day money-back guarantee (no questions asked)
- ✓ Free shipping on every order
- ✓ Cancel anytime with one click
Worst case: you get a full refund. Best case: you get better science for $0.67/day more.
What's Included
- Ergothioneine5 mg
- Taurine3.05 g
- Creatine Monohydrate5.25 g
- Glycine5 g
- Inulin4 g
- Magnesium (as Citrate)150 mg
- Glucosamine Sulfate750 mg
Directions
Mix one scoop with 8-12 oz of water or your favorite beverage. Take with your first meal of the day.
- Astaxanthin6 mg
- Lutein10 mg
- Zeaxanthin2 mg
- Coenzyme Q10200 mg
Directions
Take 1 softgel with your first meal of the day, alongside your Morning Blend.
- Lithium (as Orotate)400 mcg
- L-Theanine200 mg
- Glucosamine Sulfate750 mg
Directions
Take 2 capsules 30-60 minutes before bed with water.
- ✓Premium borosilicate glass construction
- ✓Designed for mixing your Morning Blend
- ✓Included free with your first order
- ✓Dishwasher safe
FAQ
Common questions from AG1 switchers
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